Publications of the Week Shorter Granulocyte Telomeres among Children and Adolescents with Perinatally-Acquired HIV Infection and Chronic Lung Disease in ZimbabweAjaykumar, A., et al. | August 26, 2020Chronic lung disease (CLD) has been reported among African children with perinatally-acquired HIV infection (C-PHIV),…eabramovichAugust 26, 2020 Read More
Publications of the Week Angiotensin II Type 1 Receptor Blocker Telmisartan Inhibits the Development of Transient Hypoxia and Improves Tumour Response to RadiationWadsworth, B.J., et al. | August 21, 2020This publication demonstrates how a medication normally given to individuals with high blood pressure can…eabramovichAugust 21, 2020 Read More
Publications of the Week The Epigenomics of SarcomaNacev, B.A., et al. | August 17, 2020Epigenetic regulation is critical to physiological control of development, cell fate, cell proliferation, genomic integrity…eabramovichAugust 17, 2020 Read More
Publications of the Week β1 Integrin, ILK and mTOR Regulate Collagen Synthesis in Mechanically Loaded Tendon CellsMousavizadeh, R., et al. | August 14, 2020The authors discovered that tendon cells respond to mechanical stimuli via integrins. Integrin β1 and…eabramovichAugust 14, 2020 Read More
Publications of the Week The Stringent Stress Response Controls Proteases and Global Regulators under Optimal Growth Conditions in Pseudomonas aeruginosaPletzer, D., et al. | August 13, 2020The bacterial stringent stress response, mediated by the signaling molecule guanosine tetraphosphate, ppGpp, has recently…eabramovichAugust 13, 2020 Read More
Publications of the Week Sustained Depletion of FXIII-A by Inducing Acquired FXIII-B DeficiencyStrilchuk, A.W., et al. | August 7, 2020This work, describing siRNA targeting FXIII-B (siFXIIIB), is the first pharmacologic approach for long-acting, reversible,…eabramovichAugust 7, 2020 Read More
Publications of the Week Frequency of the Loss of CAA Interruption in the HTT CAG Tract and Implications for Huntington Disease in the Reduced Penetrance RangeBlack, H.F., et al. | August 6, 2020In some Huntington disease (HD) patients, the “loss of interruption” (LOI) variant eliminates an interrupting…eabramovichAugust 6, 2020 Read More
Publications of the Week Single Cell Transcriptomes of Normal Endometrial Derived Organoids Uncover Novel Cell Type Markers and Cryptic Differentiation of Primary TumoursCochrane, D.R., et al. | July 30, 2020Endometrial carcinoma, the most common gynaecological cancer, develops from endometrial epithelium which is composed of…eabramovichJuly 30, 2020 Read More
Publications of the Week The Pathognomonic FOXL2 C134W Mutation Alters DNA Binding SpecificityCarles, A., et al. | July 28, 2020The somatic missense point mutation c.402C>G (p.C134W) in the FOXL2 transcription factor is pathognomonic for…eabramovichJuly 28, 2020 Read More
Publications of the Week Integrins Modulate Extracellular Matrix Organization to Control Cell Signaling during HematopoiesisKhadilkar, R.J., et al. | July 23, 2020The authors show that integrins play a key role during fly hematopoiesis in regulating cell…eabramovichJuly 23, 2020 Read More