Publications of the Week LIN28B Promotes the Development of Neuroendocrine Prostate CancerLovnicki, J.M., et al. | July 20, 2020Compelling evidence has shown that LIN28b plays an important role in regulating the lineage switch…eabramovichJuly 20, 2020 Read More
Publications of the Week Genetic and Evolutionary Patterns of Treatment Resistance in Relapsed B-Cell LymphomaRushton, C.K., et al. | July 17, 2020This study not only uncovers mechanisms of diffuse large B cell lymphoma (DLBCL) treatment resistance,…eabramovichJuly 17, 2020 Read More
Publications of the Week Bax and Bak Jointly Control Survival and Dampen the Early Unfolded Protein Response in Pancreatic β-Cells Under Glucolipotoxic StressWhite, S.A., et al. | July 16, 2020This work sheds new light on the molecular machinery that controls β-cell survival. The authors…eabramovichJuly 16, 2020 Read More
Publications of the Week Improved Structural Variant Interpretation for Hereditary Cancer Susceptibility Using Long-Read SequencingThibodeau, M.L., et al. | July 13, 2020The researchers employed the Oxford Nanopore PromethION long-read sequencer to re-sequence and analyze the genomes…eabramovichJuly 13, 2020 Read More
Publications of the Week AAV8 Ins1-Cre Can Produce Efficient β-Cell Recombination but Requires Consideration of Off-Target EffectsRamzy, A., et al. | July 10, 2020The Cre-LoxP system, which uses a tool borrowed from viruses, is the most prevalent technology…eabramovichJuly 10, 2020 Read More
Publications of the Week MYC-Induced Human Acute Myeloid Leukemia Requires a Continuing IL3/GM-CSF Co-StimulusBulaeva, E., et al. | July 8, 2020Hematopoietic clones with leukemogenic mutations arise in healthy people as they age, but progression to…eabramovichJuly 8, 2020 Read More
Publications of the Week Suboptimal Biological Sampling as a Probable Cause of False-Negative COVID-19 Diagnostic Test ResultsKinloch, N.N., et al. | July 6, 2020Although nasopharyngeal swabs are routinely ordered for respiratory viruses, it was long speculated that improper…eabramovichJuly 6, 2020 Read More
Publications of the Week Multi-Omic Approach to Identify Phenotypic Modifiers Underlying Cerebral Demyelination in X-Linked AdrenoleukodystrophyRichmond, P.A., et al. | July 2, 2020X-linked adrenoleukodystrophy (ALD) is a peroxisomal metabolic disorder with a highly complex clinical presentation. ALD…eabramovichJuly 2, 2020 Read More
Publications of the Week Comparative Genomics Identified a Genetic Locus in Plant-Associated Pseudomonas Spp. that Is Necessary for Induced Systemic SusceptibilityBeskrovnaya, P., et al. | June 30, 2020Read the Publication This week we profile a recent publication in mBio from the laboratory…eabramovichJune 30, 2020 Read More
Publications of the Week NPFF Increases Fusogenic Proteins Syncytin 1 and Syncytin 2 via GCM1 in First Trimester Primary Human Cytotrophoblast CellsZhu, H., et al. | June 26, 2020Neuropeptide FF (NPFF) is well-known for its roles in the central nervous system. Despite studies…eabramovichJune 26, 2020 Read More