Publications of the Week DNA Methylation Epitypes of Burkitt Lymphoma with Distinct Molecular and Clinical Features Thomas, N., et al. | August 1, 2025 The genetic subtypes of Burkitt lymphoma have been defined, but the role of epigenetics remains…karnottAugust 1, 2025 Read More
Publications of the Week CXCR4-LASP1-G9a-Snail Axis Drives NEPC Transdifferentiation via Induction of EMT and Downregulation of REST Liu, L., et al. | July 21, 2025 Phenotypic switching is an emerging driver of cancer treatment resistance, yet early signals regulating this…karnottJuly 21, 2025 Read More
Publications of the Week Drug Tolerance and Persistence to EGFR Inhibitor Treatment Are Mediated by an ILK-SFK-YAP Signaling Axis in Lung Adenocarcinoma Shi, R., et al. | July 16, 2025 Combating resistance to targeted therapy remains a major challenge to improving lung cancer care. Epithelial-mesenchymal…karnottJuly 16, 2025 Read More
Publications of the Week Widespread and Cell-Type-Specific Transcriptomic Reorganization Following Mild Traumatic Brain Injury Swaro, A., et al. | July 8, 2025 Knowledge of how traumatic brain injury (TBI) alters the brain is urgently needed. A major…karnottJuly 8, 2025 Read More
Publications of the Week Sensitivity of Diffusion Tensor Imaging to Regional Mixed Cerebrovascular Pathology Ferris, J., et al. | July 7, 2025 Diffusion tensor imaging is a candidate biomarker in cerebrovascular disease. Yet, little is known about…karnottJuly 7, 2025 Read More
Publications of the Week Cortical Effects of Dopamine Replacement Account for Clinical Response Variability in Parkinson’s Disease Wiesman, A., et al. | July 4, 2025 Individual variability in clinical response to dopamine replacement therapy (DRT) is a key barrier to…karnottJuly 4, 2025 Read More
Publications of the Week Human De Novo Mutation Rates From a Four-Generation Pedigree Reference Porubsky, D., et al. | June 23, 2025 Understanding the human de novo mutation (DNM) rate requires complete sequence information1. Here using five…karnottJune 23, 2025 Read More
Publications of the Week NOTCH1 Dimeric Signaling Is Essential for T-Cell Leukemogenesis and Leukemia Maintenance Tamiro, F., et al. | June 20, 2025 T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive malignancy that is characterized by an expansion…karnottJune 20, 2025 Read More
Publications of the Week Functional Targeting of ILC2s and ILC3s Reveals Selective Roles in Intestinal Fibrosis and Homeostasis Kabil, A., et al. | June 12, 2025 Innate lymphoid cells (ILCs) are long-lived, tissue-resident cell analogs to T helper subsets that lack…karnottJune 12, 2025 Read More
Publications of the Week Recovery of Antibody Immunity After a Resurgence of Respiratory Syncytial Virus Infections Reicherz, F., et al. | June 5, 2025 Longitudinal measurements of respiratory syncytial virus (RSV) immunity over 4 winter seasons reveal that viral…karnottJune 5, 2025 Read More