Publications of the Week Altered microRNA Expression Links IL6 and TNF-Induced Inflammaging with Myeloid MalignancyGrants, J.M., et al. | May 25, 2020This study reveals how regulation of a microRNA links aging, inflammation and the development of…eabramovichMay 25, 2020 Read More
Publications of the Week Overexpression of the Small RNA PA0805.1 in Pseudomonas aeruginosa Modulates the Expression of a Large Set of Genes and Proteins, Resulting in Altered Motility, Cytotoxicity, and Tobramycin ResistanceColeman, S.R., et al. | May 21, 2020Pseudomonas aeruginosa is a motile species that initiates swarming motility in response to specific environmental cues,…eabramovichMay 21, 2020 Read More
Publications of the Week Loss of m1acp3Ψ Ribosomal RNA Modification Is a Major Feature of CancerBabaian, A., et al. | May 19, 2020The authors found that there is a ribosomal RNA hyper-modification called 1-methyl-3-α-amino-α-carboxyl-propyl pseudouridine (macpΨ) that…eabramovichMay 19, 2020 Read More
Publications of the Week Towards Stem Cell Therapies for Skeletal Muscle RepairJudson, R.N., & Rossi, F.M.V. | May 14, 2020Skeletal muscle is an ideal target for cell therapy. The use of its potent stem…eabramovichMay 14, 2020 Read More
Publications of the Week His-Tagged Peptidiscs Enable Affinity Purification of the Membrane Proteome for Downstream Mass Spectrometry AnalysisYoung, J., et al. | May 13, 2020Detergents are not compatible with mass spectrometry, and their removal from biological samples often results…eabramovichMay 13, 2020 Read More
Publications of the Week A Sparse, Spatially Biased Subtype of Mature Granule Cell Dominates Recruitment in Hippocampal-Associated BehaviorsErwin, S.R., et al. | May 11, 2020To try and decipher how precisely granule cells of the dentate gyrus contribute to hippocampal…eabramovichMay 11, 2020 Read More
Publications of the Week ntJoin: Fast and Lightweight Assembly-Guided Scaffolding Using Minimizer GraphsCoombe, L., et al. | May 7, 2020The Bioinformatics Technology Lab at Canada’s Michael Smith Genome Sciences Centre (GSC) at BC Cancer…eabramovichMay 7, 2020 Read More
Publications of the Week Pan-Cancer Analysis of Advanced Patient Tumors Reveals Interactions Between Therapy and Genomic LandscapesPleasance, E., et al. | May 5, 2020This in-depth analysis of the first cohort from BC Cancer’s Personalized OncoGenomics Program provides a…eabramovichMay 5, 2020 Read More
Publications of the Week The miR-185/PAK6 Axis Predicts Therapy Response and Regulates Survival of Drug-Resistant Leukemic Stem Cells in CMLLin, H., et al. | April 30, 2020The authors performed global transcriptome profiling in leukemic stem/progenitor cells from treatment-naive chronic myeloid leukemia…eabramovichApril 30, 2020 Read More
Publications of the Week Intestinal Restriction of Salmonella Typhimurium Requires Caspase-1 and Caspase-11 Epithelial Intrinsic InflammasomesCrowley, S.M., et al. | April 29, 2020The authors investigated the role of the inflammasome effector caspases-1 and -11 during Salmonella enterica serovar Typhimurium…eabramovichApril 29, 2020 Read More